Oncology MCQs

General Oncology


Question 1

Patient with non-small cell lung cancer is undergoing preoperative evaluation for lobectomy. He has no history of cardiovascular or cerebrovascular events. Initial testing shows the patient’s predicted postoperative forced expiratory volume in one second (ppoFEV1) would be 36% of the expected value for his age and size based on the extent of the planned resection. Which of these subsequent tests is most likely to be useful in routine assessment of whether this patient is a candidate for lobectomy?
  • A. .
  • B. .
  • C. .
  • D. Carotid Doppler studies.

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Question 2

Your patient with stage I non-small cell lung cancer is undergoing evaluation prior to surgical resection. She has limited pulmonary reserve. Which of these surgical options is most appropriate for this patient?
  • A. Lobectomy.
  • B. Segmentectomy.
  • C. Pneumonectomy.
  • D. Wedge resection.

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Question 3

Your patient with T1 non-small cell lung cancer is diagnosed with mediastinal nodal involvement (N2) disease. He is surgically fit. Which of these treatments is most appropriate?
  • A. Lobectomy.
  • B. Wedge resection.
  • C. Chemotherapy with radiotherapy.
  • D. Lobectomy with chemotherapy alone.
  • E. None of these options.

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Question 4

Your patient is undergoing evaluation because of stage II non-small cell lung cancer with mainstem bronchus tumors that are <2 cm from the carina. She has marginal pulmonary reserve. Which of these surgical techniques is most appropriate for this patient?
  • A. Wedge resection.
  • B. Pulmonary artery sleeve resection.
  • C. Lobectomy.
  • D. Pneumonectomy.

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Question 5

A patient has been diagnosed with locally advanced non-small cell lung cancer with mediastinoscopy-negative superior sulcus tumors. He has no comorbidities or contraindications for surgery. Which of these treatments is most likely to improve survival without causing a significant increase in postoperative mortality?
  • A.
  • B. .
  • C. .
  • D. Induction chemotherapy, resection, and postoperative radiation.

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Question 6

A patient is undergoing evaluation because of suspected stage IIIA non-small cell lung cancer with possible ipsilateral mediastinal-involved lymph nodes. In addition to invasive staging with pathology, which of these tests is most appropriate for determining whether this patient is a candidate for resection?
  • A.
  • B.
  • C.
  • D. FDG-PET and CT scans.

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Question 7

A patient with bulky N2 stage IIIA non-small cell lung cancer has good performance status. Which of these treatments is most appropriate to extend this patient’s survival and avoid undue treatment risks or complications?
  • A. 
  • B.
  • C.
  • D. Platinum-based chemotherapy alone.

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Question 8

Some asthmatic patients exhibit aspirin sensitivity (and sensitivity to other NSAIDS). Daily administration of aspirin causes desensitization not only to aspirin also to other NSAIDS. This phenomenon is:
  • A. Nocebo.
  • B. Cross-tolerance.
  • C. Efficacy.
  • D. The placebo effect.
  • E. Potency.

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Question 9

Reversible Oligospermia is associated with which of the following drugs?
  • A. Methotrexate.
  • B. Sulfasalazine.
  • C. Spironolactone.
  • D. Cimetidine.
  • E. Hydrocortisone.

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Question 10

Opiate intoxication is characterized by which of the following?
  • A. Increased respiratory rate.
  • B. Hypotension.
  • C. Miosis.
  • D. Bradycardia.
  • E. All of these options.

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Question 11

A baby swallowed the contents of a 15g tube of nystatin. What should you do to remedy the over dosage?
  • A. Call an ambulance immediately.
  • B. Rush the child to emergency services.
  • C. Nothing as the dose is too low dose for the child to get any serious side effects.
  • D. Perform an immediate stomach lavage by giving the child lots of fluid.
  • E. Administer activated charcoal.

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Question 12

Nitroglycerin is used for the treatment of angina. A specific concern related to the long term use of this drug is which of the following?
  • A. Arthritic pain.
  • B. Development of A-V heart block when given with hydralazine.
  • C. Development of profound hypertension when given with sildenafil (Viagra).
  • D. Down regulation of receptor sites.
  • E. Tolerance developing requiring larger doses.

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Question 13

Grey baby syndrome occurs with which of the following drugs?
  • A. Doxycycline.
  • B. Penicillin.
  • C. Clarithromycin.
  • D. Chloramphenicol.

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General Oncology


Question 14

Following are characteristics of toxic shock syndrome, EXCEPT
  • A. diffuse macular rash.
  • B. fever/headache.
  • C. myalgia/oliguria.
  • D. increased SGOT/SGPT levels.
  • E. person to person transmission.

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Question 15

Blood tests are carried out on patients who take carbimazole, which one below is a FALSE statement?
  • A. This is so that the clinician can monitor thyroid levels.
  • B. This is so that the clinician can monitor for agranular cytosis.
  • C. This is so that the clinician can monitor for ALT.
  • D. This is so that the clinician can monitor for anaemia.
  • E. This is so that the clinician can monitor for hypoglycemia.

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Question 16

Aspirin allergy is related to?
  • A. Histamine.
  • B. Arachidonic acid.
  • C. Leukotrienes.
  • D. Bradykinin.
  • E. Serotonin.

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Question 17

Antihypertensive agents must be used with caution. The medical condition for which methyldopa is most contraindicated is:
  • A. Asthma.
  • B. Liver disease.
  • C. Mental depression.
  • D. Renal insufficiency.
  • E. Coronary insufficiency.

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Question 18

Antidote for chlorpromazine overdose is:
  • A. Naloxone.
  • B. Benztropine.
  • C. N acetylcysteine.
  • D. Ethanol.
  • E. Physostigmine.

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Question 19

Antidote for amitriptyline (Elavil) overdose is:
  • A. Naloxone.
  • B. N acetylcysteine.
  • C.Physostigmine.
  • D. Ethanol.
  • E. Atropine.

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Question 20

An alcoholic patient is being attended to in the emergency room with symptoms of alcohol toxicity. Which action should be taken?

I. infusion of multivitamin thiamine (pyridoxine 100 mg IV q day) for neurological symptoms

II diazepam for withdrawal symptoms

III phenytoin for convulsions
  • A. I, II and III.
  • B. I only.
  • C. III only.
  • D. II and III.
  • E. I and II.

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Question 21

Adverse effects of beta-2 adrenergic bronchodilators include all of the following EXCEPT:
  • A. Lethargy.
  • B. Nervousness.
  • C. Headache.
  • D. Tremulousness.
  • E. Tachycardia.

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Question 22

Adverse effect(s) of laxatives:
  • A. Dehydration.
  • B. Spastic colitis with stimulant laxatives.
  • C. Gastrointestinal obstruction with bulk forming agents.
  • D. Electrolyte disturbances (hypernatremia, hypokalemia).
  • E. All of these options.

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Question 23

Acetaminophen (Tylenol) overdose is treated with:
  • A. Naloxone.
  • B. N-acetylcysteine.
  • C. Enteric charcoal.
  • D. IV fluids.
  • E. All of these options.

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Question 24

A woman phoned you whilst running a busy afternoon clinic. She told you that her husband has swallowed 30 tablets of acetaminophen/paracetamol 325mg. What is the proper advice?
  • A. He will be all right, he should not worry and this not a serious concern.
  • B. Call drug information center for help.
  • C. Induce emesis-using ipecac.
  • D. Call the poison center to ask for advice.
  • E. Refer him to the emergency department.

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Question 25

A patient complains of headache and his blood pressure is 120/80. His medications include hydrochlorothiazide and hydralazine. Which of the following would seem most likely?
  • A. The headaches are related to hydralazine-induced agranulocytosis.
  • B. The headaches are secondary to thiazide-induced hypokalemia.
  • C. The headaches are secondary to hydralazine therapy.
  • D. The headaches are caused by an temporary increased blood pressure.
  • E. The headaches are probably unrelated to drug therapy.

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Question 26

A doctor and nurse start frantically looking for naloxone for a female patient is suspected of overdosing of IV narcotics. What basic principle in the treatment of poisoning are they overlooking?
  • A. Electrolytes.
  • B. Syrup of ipecac.
  • C. Blood analysis.
  • D. Gastric lavage.
  • E. Control of vital functions.

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Question 27

A child has ingested an unknown substance and has evidence of respiratory depression. This symptom is usually found with poisoning due to:
  • A. Amphetamines.
  • B. Kerosene.
  • C. Atropine.
  • D. Opioids.
  • E. Mushrooms.

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